AKI - human studies
نویسندگان
چکیده
منابع مشابه
Therapeutic Targets of Human AKI: Harmonizing Human and Animal AKI.
The opportunity to make advances in the prevention and treatment of AKI has never been greater than it is today. Major advances have been made in the understanding of the biology of AKI, the design of clinical trials, and the use of diagnostic and prognostic biomarkers. These advances have been supplemented by the coordinated effort of societies, federal agencies, and industry, such that we are...
متن کاملHuman AKI and heme oxygenase-1.
Findings derived from animal models of AKI gain clinical credence and appeal when translational studies corroborate their occurrence in human AKI. In the current issue of JASN, Zager et al. take important steps in addressing the clinical applicability of the conclusion drawn from animal models that induction of heme oxygenase-1 (HO-1) is a protective response in AKI. The major heme-degrading me...
متن کاملSubclinical AKI is still AKI
The concept of acute kidney syndromes has shifted in recent years from acute renal failure to acute kidney injury (AKI). AKI implies injury or damage but not necessarily dysfunction. The human kidney has an important glomerular function reserve, and dysfunction becomes evident only when more than 50% of the renal mass is compromised. Recent AKI classifications include even slight changes in ser...
متن کاملAKI: a path forward.
The Kidney Research National Dialogue, supported by the National Institute of Diabetes and Digestive and Kidney Diseases, asked the scientific community to formulate and prioritize research objectives that would improve our understanding of kidney function and disease. High-priority objectives for AKI were identified, including enhancing training and collaborative opportunities, improving pheno...
متن کاملPredictors of Recurrent AKI.
Recurrent AKI is common among patients after hospitalized AKI and is associated with progressive CKD. In this study, we identified clinical risk factors for recurrent AKI present during index AKI hospitalizations that occurred between 2003 and 2010 using a regional Veterans Administration database in the United States. AKI was defined as a 0.3 mg/dl or 50% increase from a baseline creatinine me...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2013
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gft129